![The HOT-ICU Trial: Lower vs Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure - REBEL EM - Emergency Medicine Blog The HOT-ICU Trial: Lower vs Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure - REBEL EM - Emergency Medicine Blog](https://rebelem.com/wp-content/uploads/2021/03/HOT-ICU-1024x575.png)
The HOT-ICU Trial: Lower vs Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure - REBEL EM - Emergency Medicine Blog
![Critical Care Alert: Conservative Oxygen Therapy in Mechanically Ventilated Patients - the ICU-ROX Study EMRA Critical Care Alert: Conservative Oxygen Therapy in Mechanically Ventilated Patients - the ICU-ROX Study EMRA](https://www.emra.org/siteassets/emresident/images/articles/2020/02/icu-rox.jpg)
Critical Care Alert: Conservative Oxygen Therapy in Mechanically Ventilated Patients - the ICU-ROX Study EMRA
![Diagnostics | Free Full-Text | Management of COVID-19-Associated Acute Respiratory Failure with Alternatives to Invasive Mechanical Ventilation: High-Flow Oxygen, Continuous Positive Airway Pressure, and Noninvasive Ventilation Diagnostics | Free Full-Text | Management of COVID-19-Associated Acute Respiratory Failure with Alternatives to Invasive Mechanical Ventilation: High-Flow Oxygen, Continuous Positive Airway Pressure, and Noninvasive Ventilation](https://www.mdpi.com/diagnostics/diagnostics-11-02259/article_deploy/html/images/diagnostics-11-02259-g001.png)
Diagnostics | Free Full-Text | Management of COVID-19-Associated Acute Respiratory Failure with Alternatives to Invasive Mechanical Ventilation: High-Flow Oxygen, Continuous Positive Airway Pressure, and Noninvasive Ventilation
Managing Oxygen Therapy in the ICU | Providing supplemental oxygen in the ICU often exposes patients to a high Fio2 and a higher-than-normal Pao2, which have been associated with increased... | By
![Liberal or conservative oxygen therapy for ventilated patients in the ICU: a meta-analysis of randomized controlled trials | Journal of Cardiothoracic Surgery | Full Text Liberal or conservative oxygen therapy for ventilated patients in the ICU: a meta-analysis of randomized controlled trials | Journal of Cardiothoracic Surgery | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13019-021-01634-4/MediaObjects/13019_2021_1634_Fig3_HTML.png)
Liberal or conservative oxygen therapy for ventilated patients in the ICU: a meta-analysis of randomized controlled trials | Journal of Cardiothoracic Surgery | Full Text
![The LOCO2 Trial: Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome - REBEL EM - Emergency Medicine Blog The LOCO2 Trial: Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome - REBEL EM - Emergency Medicine Blog](https://rebelem.com/wp-content/uploads/2020/06/LOCO2-Trial.png)
The LOCO2 Trial: Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome - REBEL EM - Emergency Medicine Blog
![Blogshot. CD013708. Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome- a rapid review September 2020 - Evidently Cochrane Blogshot. CD013708. Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome- a rapid review September 2020 - Evidently Cochrane](https://www.evidentlycochrane.net/wp-content/uploads/2020/09/Blogshot.-CD013708.-Oxygen-targets-in-the-intensive-care-unit-during-mechanical-ventilation-for-acute-respiratory-distress-syndrome-a-rapid-review-September-2020.png)
Blogshot. CD013708. Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome- a rapid review September 2020 - Evidently Cochrane
![Conservative oxygen therapy for critically ill patients: a meta-analysis of randomized controlled trials | Journal of Intensive Care | Full Text Conservative oxygen therapy for critically ill patients: a meta-analysis of randomized controlled trials | Journal of Intensive Care | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs40560-021-00563-7/MediaObjects/40560_2021_563_Fig2_HTML.png)
Conservative oxygen therapy for critically ill patients: a meta-analysis of randomized controlled trials | Journal of Intensive Care | Full Text
![Less is more: Conservative Oxygen Therapy during Mechanical Ventilation in the ICU — MRINZ - Medical Research Institute of New Zealand Less is more: Conservative Oxygen Therapy during Mechanical Ventilation in the ICU — MRINZ - Medical Research Institute of New Zealand](https://images.squarespace-cdn.com/content/v1/5e9e7873f15ec443bd66cd3c/1588650205413-MJOZUET9Z3D4G33EG3YL/ICU-ROX-editorial-v06-by-Dr-Cilein-Kearns-72dpi-640px.jpg)
Less is more: Conservative Oxygen Therapy during Mechanical Ventilation in the ICU — MRINZ - Medical Research Institute of New Zealand
![PDF] Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX). | Semantic Scholar PDF] Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX). | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/e35967c6f64dfc5e3473cd6ca68406ae1ca96830/2-Table1-1.png)
PDF] Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX). | Semantic Scholar
![Frontiers | The Effect of Conservative Oxygen Therapy in Reducing Mortality in Critical Care Patients: A Meta-Analysis and Trial Sequential Analysis Frontiers | The Effect of Conservative Oxygen Therapy in Reducing Mortality in Critical Care Patients: A Meta-Analysis and Trial Sequential Analysis](https://www.frontiersin.org/files/Articles/738418/fmed-08-738418-HTML/image_m/fmed-08-738418-g001.jpg)
Frontiers | The Effect of Conservative Oxygen Therapy in Reducing Mortality in Critical Care Patients: A Meta-Analysis and Trial Sequential Analysis
![Blogshot. CD013708. Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome- a rapid review. EENursing. September 2020 - Evidently Cochrane Blogshot. CD013708. Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome- a rapid review. EENursing. September 2020 - Evidently Cochrane](https://www.evidentlycochrane.net/wp-content/uploads/2020/09/Blogshot.-CD013708.-Oxygen-targets-in-the-intensive-care-unit-during-mechanical-ventilation-for-acute-respiratory-distress-syndrome-a-rapid-review.-EENursing.-September-2020.png)
Blogshot. CD013708. Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome- a rapid review. EENursing. September 2020 - Evidently Cochrane
![Conservative oxygen therapy for mechanically ventilated adults with suspected hypoxic ischaemic encephalopathy. - Abstract - Europe PMC Conservative oxygen therapy for mechanically ventilated adults with suspected hypoxic ischaemic encephalopathy. - Abstract - Europe PMC](https://europepmc.org/articles/PMC7431900/bin/134_2020_6196_Fig1_HTML.jpg)
Conservative oxygen therapy for mechanically ventilated adults with suspected hypoxic ischaemic encephalopathy. - Abstract - Europe PMC
![Protocol and statistical analysis plan for the mega randomised registry trial research program comparing conservative versus liberal oxygenation targets in adults receiving unplanned invasive mechanical ventilation in the ICU (Mega-ROX) | CCR Protocol and statistical analysis plan for the mega randomised registry trial research program comparing conservative versus liberal oxygenation targets in adults receiving unplanned invasive mechanical ventilation in the ICU (Mega-ROX) | CCR](https://ccr.cicm.org.au/cicm-ccr/media/Images/2022/June%202022/140_figure2.jpg)